Recombinant Human BD-1 (47 a.a.)

$70.00$2,700.00

 

Catalog Number:P1021-5ug
                                   P1021-20ug
                                   P1021-1mg

Description:

Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system.  The α-defensins are distinguished from the β-defensins by the pairing of their three disulfide bonds.  To date, six human β-defensins have been identified; BD-1, BD-2, BD-3, BD-4, BD-5 and BD-6.  β-defensins are expressed on some leukocytes and at epithelial surfaces.  In addition to their direct antimicrobial activities, they can act as chemoattractants towards immature dendritic cells and memory T cells.  The β-defensin proteins are expressed as the C-terminal portion of precursors, and are released by proteolytic cleavage of a signal sequence and, in some cases, a propeptide sequence.  β-defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds.  Recombinant Human BD-1 is a 5.0 kDa protein containing 47 amino acid residues.

Source:E.coli

Synonyms:Beta-Defensin 1, DEFB1, HBD1

AA Sequence:GNFLTGLGHR SDHYNCVSSG GQCLYSACPI FTKIQGTCYR GKAKCCK

Purity:≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity:

Determined by its ability to chemoattract CD34+ dendritic cells using a concentration range of 100.0-1000.0 ng/ml.

Cross Reactivity:Human

Usage: FOR RESEARCH USE ONLY.

Note:The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

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SKU: P1021 Category:

Additional information

Size

5ug, 20ug, 1mg

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