Recombinant Human BD-3

$70.00$2,700.00

Catalog Number:P1025-5ug
                                   P1025-20ug
                                   P1025-1mg

Description:

Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system.  The α-defensins are distinguished from the β-defensins by the pairing of their three disulfide bonds.  To date, six human β-defensins have been identified; BD-1, BD-2, BD-3, BD-4, BD-5 and BD-6.  β-defensins are expressed on some leukocytes and at epithelial surfaces.  In addition to their direct antimicrobial activities, they can act as chemoattractants towards immature dendritic cells and memory T cells.  The β-defensin proteins are expressed as the C-terminal portion of precursors, and are released by proteolytic cleavage of a signal sequence and, in some cases, a propeptide sequence.  β-defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds.  Recombinant Human BD-3 is a 5.1 kDa protein containing 45 amino acid residues.

Source:E.coli

Synonyms:Beta-Defensin 3, DEFB3, DEFB103A

AA Sequence:GIINTLQKYY CRVRGGRCAV LSCLPKEEQI GKCSTRGRKC CRRKK

Purity:≥ 98% by SDS-PAGE gel and HPLC analyses. 

Biological Activity:Exhibits antimicrobial activity against gram-positive bacteria S. aureus and gram-negative P. aeruginosa and E.coli.

Cross Reactivity:Bacteria, Human, Mouse, N/A, Virus

Usage:FOR RESEARCH USE ONLY

Note:The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Clear
SKU: P1025 Category:

Additional information

Size

5ug, 20ug, 1mg