Recombinant Human GM-CSF

$70.00$2,925.00

Catalog Number:P1152-5ug
                                   p1152-20ug
                                   p1152-1mg

Description:

GM-CSF is a hematopoietic growth factor that stimulates the development of neutrophils and macrophages, and promotes the proliferation and development of early erythroid megakaryocytic and eosinophilic progenitor cells. It is produced in endothelial cells, monocytes, fibroblasts and T-lymphocytes. GM-CSF inhibits neutrophil migration and enhances the functional activity of the mature end-cells. The human and murine molecules are species-specific and exhibit no cross-species reactivity. Recombinant Human GM-CSF is a 14.6 kDa globular protein consisting of 128 amino acids, containing two intramolecular disulfide bonds and two potential N-linked glycosylation sites.

Source:E.coli

Synonyms:Granulocyte-Macrophage Colony-Stimulating Factor, CSF-2, MGI-1GM, Pluripoietin-α

AA Sequence:

MAPARSPSPS TQPWEHVNAI QEARRLLNLS RDTAAEMNET VEVISEMFDL QEPTCLQTRL ELYKQGLRGS LTKLKGPLTM MASHYKQHCP PTPETSCATQ IITFESFKEN LKDFLLVIPF DCWEPVQE

Purity:Greater than 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity:

The ED50 as determined by the dose-dependent stimulation of the proliferation of human TF-1 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 107 units/mg.

Cross Reactivity:Bacteria, Chicken, Human, Human + Mouse, Leech, Mouse, Pig

Usage:FOR RESEARCH USE ONLY

Note:The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

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SKU: P1152 Category:

Additional information

Size

5ug, 20ug, 1mg

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