Recombinant Human IFN-γ

$70.00$990.00

Catalog Number:P1183-20ug
                                   p1183-100ug
                                   p1183-1mg

Description:

IFN-γ is an acid-labile interferon produced by CD4 and CD8 T lymphocytes as well as activated NK cells.  IFN-γ receptors are present in most immune cells, which respond to IFN-γ signaling by increasing the surface expression of class I MHC proteins.  This promotes the presentation of antigen to T-helper (CD4+) cells.  IFN-γ signaling in antigen-presenting cells, and antigen-recognizing B and T lymphocytes, regulates the antigen-specific phases of the immune response.  Additionally, IFN-γ stimulates a number of lymphoid cell functions, including the anti-microbial and anti-tumor responses of macrophages, NK cells, and neutrophils.  Human IFN-γ is species-specific and is biologically active only in human and primate cells.  Recombinant Human IFN-γ is a 16.8 kDa protein containing 144 amino acid residues.

Source:E.coli

Synonyms:Immune Interferon, type II interferon, T cell interferon, MAF

AA Sequence:

MQDPYVKEAE NLKKYFNAGH SDVADNGTLF LGILKNWKEE SDRKIMQSQI VSFYFKLFKN FKDDQSIQKS VETIKEDMNV KFFNSNKKKR DDFEKLTNYS VTDLNVQRKA IHELIQVMAE LSPAAKTGKR KRSQMLFQGR RASQ

Purity:≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity:

The ED50 determined by a cytotoxicity assay using HT-29 cells is ≤ 0.05 ng/ml, corresponding to a specific activity of ≥ 2 x 107units/mg.

Cross Reactivity:Fish + Virus, Human, Human + Bacteria, Human + Mouse, Human + Virus, Leech, Mandarin Fish, Monkey, Mouse, N/A, Pig, Ra

Usage: FOR RESEARCH USE ONLY.

Note:The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

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SKU: P1183 Category:

Additional information

Size

20ug, 100ug, 1mg

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