Recombinant Human Neuritin

$70.00$2,700.00

Catalog Number:P2004-5ug
                                   P2004-20ug
                                   P2004-1mg

Description:

Neuritin (NRN1) is a neurotrophic factor, which is expressed in response to induction of neuronal activity by NGF, BDNF, NT3 and other neural stimulators. NRN1 is expressed principally in postmitotic-differentiating neurons of the developing nervous system and in neuronal structures related to synaptic plasticity in the adult nervous system. NRN1 functions as a molecular mediator of neurite outgrowth, neuronal survival, and synaptic maturation.Recombinant Human NRN1 produced in E.coli cells is a non-glycosylated, homodimeric protein containing 2×88 amino acid chains and having a molecular mass of 19.4kDa.
The NRN1 is purified by proprietary chromatographic techniques.

Source:E.coli

Synonyms:Neuritin 1, NRN1, NRN, dJ380B8.2, Neuritin.

AA Sequence :

AGKCDAVFKG FSDCLLKLGD SMANYPQGLD DKTNIKTVCT YWEDFHSCTV TALTDCQEGA KDMWDKLRKE SKNLNIQGSL FELCGSGN.

Purity:

Greater than 95.0% as determined by:
(a) Analysis by RP-HPLC.
(b) Analysis by SDS-PAGE.

Biological Activity:

The ED50 as determined by a cell proliferation assay using rat C6 cells is less than 25ng/ml, corresponding to a specific activity of > 4.0 × 104 IU/mg.

Usage:FOR RESEARCH USE ONLY

Note:The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

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SKU: P2004 Category:

Additional information

Size

5ug, 20ug, 1mg